SuperHuman Pre-Workouts Go All Red

Alpha Lion constructed its status on SuperHuman, the pre-workout household that put the model on the map. Now the complete lineup is getting a head-to-toe rebuild, and the model is leaning exhausting into a brand new thought: the change.

On Alpha Lion’s authentic black-label lineup, the merchandise have been about constructing functionality. The brand new crimson SuperHuman lineup is about “flipping a change”: activation vitality, on demand, throughout 5 completely different flavors of depth. On Episode #228 of the PricePlow Podcast, Alpha Lion’s VP of Gross sales, Darin Decker, walked by the complete relaunch with us, and the story behind the mentality is a enjoyable one. Longtime staffers on the Alpha Lion staff hint it again to a line from a basic Sylvester Stallone arm-wrestling film “Over the High”, the place flipping a hat backwards means it is time to get critical. That is the vitality (actually) behind the brand new branding.

Flip The Swap with the SuperHuman Pre-Exercise of Your Selection

Beneath the brand new crimson tubs, the modifications go deeper than shade. What was once Alpha Lion’s SXT Vitality System is now the SUPERHUMAN ENERGY® System, with retooled caffeine ratios throughout the board. Each label within the line can also be standardized to a clear 21 servings, disposing of the previous 42/21 split-scoop panels that made efficient dosing extra complicated than it wanted to be. Synthetic colours are gone throughout the board as properly.

5 Merchandise for 5 Activation States

This is the lineup, every one constructed round a unique change: SuperHuman Authentic is the each day driver, SuperHuman Excessive is the high-stim possibility for when a traditional scoop will not reduce it, SuperHuman Jacked is constructed round a dual-peptide muscle-building stack, SuperHuman Burn retains its fat-burning formulation precisely as-is, and SuperHuman Pump is the stim-free, hydration-and-focus possibility for late-day coaching. All 5 land at an ordinary mid-tier pre-workout worth level at retailers like GNC and Vitamin Shoppe.

We’ll begin with the formulation getting the deepest breakdown immediately: SuperHuman Authentic. First, join PricePlow’s Alpha Lion information alerts, after which let’s flip the change to science mode.

SuperHuman Authentic: The Each day Driver Swap

The OG SuperHuman is Alpha Lion’s on a regular basis pre-workout, one constructed for coaching you may truly repeat 5 – 6 days every week quite than saving for a single max-effort session. It is a full-label formulation with no proprietary blends, affordably priced, and each dose is printed and accounted for beneath.

Every 17.8g scoop (1 serving) supplies:

L-Citrulline – 4,000mg

L-Citrulline is a non-essential amino acid the kidneys convert into L-arginine, the substrate that nitric oxide synthase makes use of to supply nitric oxide, driving the vasodilation behind a pre-workout pump.[1] Not like arginine itself, citrulline skips first-pass metabolism within the liver and intestine, making it the extra dependable strategy to elevate circulating arginine. SuperHuman Authentic makes use of a full 4,000mg of pure L-citrulline quite than citrulline malate, so the complete dose lands as citrulline with no malic acid diluting the label declare.

A meta-analysis restricted to acute doses of three grams or extra taken earlier than coaching discovered important enchancment in energy and energy output,[2] and a separate crossover trial discovered 6 grams of citrulline improved time to exhaustion and complete work accomplished throughout high-intensity biking.[3]

At this level, we all know it and love the ingredient, and in case you want extra, there are different choices mentioned beneath that may go even larger.

Beta-Alanine – 3,200mg

Beta-Alanine combines with the amino acid histidine to type carnosine, a dipeptide saved in skeletal muscle that buffers the hydrogen ions answerable for the burning sensation and pH drop throughout high-intensity coaching.[4] At 3,200mg, SuperHuman Authentic lands proper within the well-studied each day vary proven to lift muscle carnosine over a number of weeks of constant use. A meta-analysis of 40 research discovered a big total efficiency profit, with the biggest results in efforts lasting 30 seconds to 10 minutes, precisely the place most working units and finishers dwell.[5]

After all, everyone knows the tingles by now: The one persistently reported facet impact is paresthesia, the innocent tingling some folks really feel of their pores and skin shortly after dosing.[4]

Betaine Anhydrous – 2,500mg

Betaine, also referred to as trimethylglycine, works two methods: as an osmolyte that helps cells maintain onto water underneath train stress, and as a methyl donor that feeds the conversion of homocysteine again into methionine.[6] SuperHuman Authentic’s 2,500mg dose sits at the usual analysis degree utilized in most efficiency trials.

A 2024 meta-analysis of 17 research discovered a big total energy profit from persistent betaine use, pushed primarily by lower-body energy beneficial properties, although the authors famous the impact dimension was fragile and did not maintain up throughout each sensitivity evaluation they ran.[7] Betaine wants days to weeks of constant use to construct up in tissue, so do not anticipate an acute one-scoop impact the best way you’ll from caffeine or citrulline.

L-Tyrosine – 1,500mg

L-Tyrosine is the amino acid precursor to the catecholamines dopamine and norepinephrine, and the enzyme that makes this conversion, tyrosine hydroxylase, is not absolutely saturated with substrate underneath regular situations.[8] That is helpful as a result of when demand on these pathways spikes (like throughout a tough/tense coaching session), supplemental tyrosine may also help maintain catecholamine output from working low.

A overview of the analysis persistently finds this profit exhibits up underneath actual stress or cognitive load, however not at relaxation, which traces up with why it is positioned right here as a pre-workout ingredient quite than an on a regular basis nootropic.[9] A speedy proof evaluation of the obtainable trials reached the same conclusion for cognitive efficiency underneath environmental and bodily stressors.[10]

Agmatine Sulfate – 1,000mg

Agmatine types when the physique decarboxylates L-arginine, putting it on the similar metabolic crossroads because the nitric oxide synthase pathway that citrulline and arginine additionally feed into.[11] That shared pathway is the mechanistic rationale for together with agmatine sulfate in a pump-focused stack, although the human analysis base for agmatine is mostly within the temper, ache, and neuroprotection departments quite than train or pump-specific trials.

With that mentioned, animal analysis has proven agmatine shifts vascular nitric oxide signaling towards the useful endothelial type of the enzyme whereas suppressing the inflammatory inducible type after vascular damage,[12] which helps the mechanism with out but confirming a direct human efficiency profit on the 1,000mg dose used right here.

Taurine – 1,000mg

Taurine is without doubt one of the most plentiful free amino acids in skeletal muscle, the place it helps regulate cell quantity and calcium dealing with throughout contraction.[13] A 3-level meta-analysis of 23 randomized trials discovered {that a} single acute dose of 1 to six grams produced a small-to-moderate enchancment in train efficiency, with the clearest results in cardio endurance and energy or energy duties.[14] At 1,000mg, SuperHuman Authentic’s dose sits on the decrease finish of that studied vary. Taurine and betaine are each osmolytes working by overlapping mechanisms right here, so staying hydrated issues greater than typical when a formulation leans this closely on cell-volume-related components.

Choline (from VitaCholine® Choline L(+) Bitartrate) – 500mg, offering 200mg Choline (37% DV)

Choline is the direct precursor to acetylcholine, the neurotransmitter answerable for communication on the neuromuscular junction and for cognitive capabilities tied to consideration and motor management. You will see choline listed twice on the label: the 200mg determine is the basic choline quantity used to calculate %DV, whereas the 500mg VitaCholine® line is the branded choline L(+) bitartrate supply that provides it.

These describe one ingredient counted two methods, not two separate choline sources, since 500mg of choline bitartrate works out to virtually precisely 200mg of elemental choline as soon as the bitartrate salt weight is subtracted. In a placebo-controlled trial, 2 grams of choline bitartrate improved visuomotor accuracy and produced measurable pupil constriction, a biomarker of central cholinergic exercise, about 70 minutes after ingestion.[15]

Analysis usually exhibits that exhaustive train depletes acetylcholine, and it is good to “refill the financial institution” to proceed feeling SuperHuman. You may study extra about VitaCholine in Episode #216 with Balchem’s Tom Druke.

SUPERHUMAN ENERGY® System: Caffeine Anhydrous, zümXR® Prolonged Launch & zümXR® Delayed Launch – 325mg Complete Caffeine

Caffeine works primarily by blocking adenosine receptors within the mind and physique, the identical receptors that construct up all through the day and make you’re feeling drained, and blocking them drives caffeine’s results on alertness, focus, and lowered perceived effort throughout train.[16]

SuperHuman Authentic splits its 325mg complete caffeine yield throughout three launch profiles quite than counting on anhydrous alone: 275mg hits instantly, whereas 41mg of zümXR® Prolonged Launch and 26mg of zümXR® Delayed Launch are engineered to launch their caffeine later, extending the curve as a substitute of letting it spike and crash.

There is not but any unbiased medical analysis particular to zümXR’s launch kinetics, nevertheless it’s very simply felt (particularly that delayed launch pop). So deal with the prolonged and delayed timing because the model’s formulation design quite than a clinically-verified pharmacokinetic curve. The general 3mg to 6mg per kilogram of body weight vary proven to reliably enhance endurance, energy, and energy efficiency is properly lined right here for many bodyweights.[16]

Vincamine – 10mg

Vincamine is an alkaloid derived from the Vinca minor periwinkle plant, and it has been used clinically in Europe for many years as a cerebral vasodilator meant to assist blood movement to the mind.[17]

Medical analysis on vincamine has usually used doses within the 30mg to 60mg vary, properly above the 10mg included right here, so it is a supporting nootropic contact alongside the caffeine and B-vitamins quite than a clinically-dosed standalone ingredient. On our podcast with Darin, he advised us Alpha Lion added vincamine throughout a number of SuperHuman formulation particularly for the blood-flow-to-the-brain angle, aiming to amplify the nootropic and focus expertise relative to the model’s earlier formulation.

In the event you’re feeling extra SuperHuman than with earlier formulation, there is a good probability that this, mixed with VitaCholine, is why.

Black Pepper Extract (95% Piperine) – 10mg

Black Pepper Extract, standardized right here to 95% piperine, is included as an absorption enhancer quite than an lively ingredient in its personal proper. The basic supporting analysis comes from a curcumin bioavailability research, the place 20mg of piperine elevated curcumin’s bioavailability in human volunteers by 2,000%.[18] That particular result’s about curcumin quite than the opposite actives on this formulation, nevertheless it’s the mechanism piperine is greatest identified for: inhibiting the liver and intestine enzymes answerable for breaking compounds down earlier than they attain circulation. At 10mg, SuperHuman Authentic doubles the 5mg dose used within the model’s earlier formulation.

Niacin – 17mg NE (106% DV)

Niacin is a B-vitamin your physique converts into NAD+ and NADP+, the coenzymes that drive tons of of energy-producing reactions in practically each cell, together with the pathways that gasoline a coaching session.[19] SuperHuman Authentic makes use of niacin as inositol hexanicotinate, a slower-converting ester type related to much less of the pores and skin flush some folks get from high-dose nicotinic acid. At 17mg, this dose sits properly inside commonplace B-vitamin assist territory quite than the multi-gram vary utilized in ldl cholesterol analysis, so consider it as rounding out the energy-metabolism facet of the label quite than a standalone lively.

A Completely different Type of Niacin Than Regular!

Curiously, that is coming from inositol hexanicotinate, a unique supply than the usual nicotinic acid (flush niacin) or niacinamide variations we usually see.

Inositol hexanicotinate is one other “flush-free” type of niacin wherein six nicotinic acid molecules are esterified to an inositol spine. It is designed to launch niacin extra regularly than free nicotinic acid, probably decreasing the attribute pores and skin flushing related to standard niacin. Those that like nicotinic acid over niacinamide (which actually simply comes from a “recycling pathway” of kinds) however don’t need the flush could get pleasure from this way more.

Vitamin B6 – 50mg (2941% DV)

Vitamin B6 turns into the coenzyme pyridoxal-5′-phosphate (PLP) as soon as metabolized, and PLP-dependent enzymes deal with amino acid metabolism together with the synthesis of neurotransmitters together with dopamine, serotonin, and GABA.[20]

SuperHuman Authentic makes use of the pyridoxine HCl type at 50mg, properly above the RDA and in keeping with doses utilized in stress and temper analysis, although not but on the ranges related to toxicity. As a result of B6 exhibits up in numerous multivitamins and vitality merchandise, it is price monitoring your complete each day consumption throughout all the things you’re taking, since chronically excessive cumulative doses have been linked to nerve-related negative effects in case experiences.[21]

Vitamin B12 – 500mcg (20833% DV)

Vitamin B12 helps crimson blood cell formation and is a coenzyme within the methionine cycle, and low standing is a well-documented driver of fatigue. SuperHuman Authentic delivers 500mcg as methylcobalamin, properly past the RDA. In athletes particularly, analysis on hemoglobin formation has discovered that advantages plateau as soon as serum B12 reaches a wholesome vary, which means extra is not essentially higher in case you’re not poor to start with.[22] Remoted B12 hasn’t proven robust standalone ergogenic results in individuals who aren’t poor,[23] however a 28-day protocol combining B1, B2, B6, and B12 improved time to exhaustion and lowered exercise-induced lactate and ammonia buildup versus placebo, supporting its function right here as a part of a broader B-vitamin stack.[24]

Flavors Out there

Authentic launches in Lion Blood (Crimson Gummy Bear), carrying over the flavour profile Alpha Lion constructed its status on, alongside the rainbow-profile taste now referred to as Flexual Therapeutic, beforehand often called Unicorn Juice. This is an up-to-date checklist of all Alpha Lion SuperHuman Authentic flavors:

What’s New, What’s Modified

SuperHuman Authentic is not an all-new formulation a lot as a rebuild of the model Alpha Lion offered proper earlier than this relaunch. Evaluating label to label, here is what’s completely different:

Vitality system renamed and retooled: The previous SXT™ Vitality System is now the SuperHuman Vitality System. The 275mg of immediate-hit Caffeine Anhydrous carries over fully unchanged, however each timed-release elements acquired a bump: zümXR® Prolonged Launch goes from 30mg to 41mg and zümXR® Delayed Launch goes from 20mg to 26mg. Complete caffeine yield climbs from 311mg to 325mg, a modest improve concentrated totally within the sustained tail of the curve quite than the preliminary hit.
SantEnergy™ Nu is gone: The earlier formulation carried 400mg of this Eriodictyon californicum extract. It did not make the reduce within the new model, however has been saved in SuperHuman Burn.
A brand new B-vitamin and nootropic stack was added as an alternative: A singular type of niacin, very excessive dose Vitamin B6, Vitamin B12, Choline (as Vitacholine®), Agmatine Sulfate, and Vincamine are all new to this formulation.
The core amino and pump stack is untouched: L-Citrulline (4,000mg), Beta-Alanine (3,200mg), Betaine Anhydrous (2,500mg), L-Tyrosine (1,500mg), Taurine (1,000mg), and Black Pepper Extract (10mg) all carry over at an identical doses from the earlier formulation.
Serving dimension simplified: The previous label confirmed two serving counts on one panel, 42 servings at a half scoop (8.2g) or 21 servings at a full scoop (16.4g). The brand new label exhibits one clear 17.8g scoop as 1 of 21 servings, no half-scoop math required.
Synthetic colours eliminated throughout the board, with Alpha Lion saying taste profiles carry over unchanged regardless of the formulation work.

The web impact: the core amino and pump spine stays precisely the place it was, the vitality system will get a modest, back-loaded caffeine improve, and a swapped-in B-vitamin and focus stack takes the place of the only botanical extract that used to spherical out the label.

SuperHuman Excessive: The Excessive-Stim Swap

Excessive is Alpha Lion’s website-exclusive ceiling formulation, constructed for stimulant veterans who’ve constructed a tolerance to straightforward pre-workouts and need one thing to truly push in opposition to.

Excessive shares its basis with Authentic, however the ratios shift towards the aggressive finish. L-Citrulline jumps to six,000mg (up from Authentic’s 4,000mg) and L-Tyrosine climbs to 2,000mg (up from 1,500mg), whereas Niacin (12mg) and Vitamin B6 (28mg) each are available in decrease than Authentic’s doses. Taurine drops out of the formulation totally, which is smart (it may possibly clean out caffeine, however Excessive customers could not need that).

Betaine Anhydrous, Beta-Alanine, Agmatine Sulfate, Vitamin B12, Choline, Vincamine, and Black Pepper Extract all carry over on the similar doses lined within the Authentic breakdown above, so we can’t repeat the science on these right here.

The headline change is caffeine: Excessive’s SUPERHUMAN ENERGY® System delivers 376mg complete, about 50mg greater than Authentic, plus 4 components Authentic would not contact in any respect.

Bitter Orange Extract (min. 25% p-Synephrine) – 120mg

Bitter Orange Extract, standardized to a minimal of 25% p-synephrine, provides no less than 30mg of the compound right here. Synephrine shares some structural similarity to ephedrine, which raised early security questions, however essentially the most complete human overview to this point concludes that at generally used doses it would not produce the stimulant-like cardiovascular results that similarity implies, based mostly on roughly 30 human research and about 360 topics.[25]

Its major studied profit is elevated fats oxidation throughout train, with human trials displaying acute doses of 2mg to 3mg per kilogram of body weight elevating the speed of fats burned throughout moderate-to-hard cardio.[26] It is positively for the extra “excessive” customers, who’re keen to tackle the upper metabolic depth.[27]

That is precisely the type of formulation Alpha Lion recommends beginning with a partial scoop to evaluate tolerance.

Ivy Extract (std. 10% Hederacosides) – 100mg

Ivy Extract, standardized to 10% hederacosides, is a well-studied European natural treatment, most frequently as a cough syrup ingredient for acute bronchitis, backed by a postmarketing security research of practically 10,000 sufferers and a number of randomized trials displaying it reduces cough severity.[28] That respiratory analysis base would not translate on to a pre-workout use case, however there’s some attention-grabbing stuff at play right here: one lab research wanting particularly at ivy’s impact on adrenergic receptors discovered that alpha-hederin, a unique ivy compound, affected beta-2 receptor habits, whereas hederacoside C, the compound truly standardized on this label, confirmed no such impact.[29]

We could not discover exercise-specific human analysis on ivy extract, so deal with this one as a conventional respiratory-support botanical using alongside in a high-stim formulation quite than a efficiency ingredient with its personal monitor document. With that mentioned… there may positively be some added stimulatory habits right here, relying on what else is within the standardization.

Huperzia Serrata Extract (1% Huperzine-A) – 20mg

Huperzia Serrata Extract, standardized to 1% Huperzine-A, supplies about 0.2mg (200mcg) of the lively alkaloid. Huperzine-A works by inhibiting acetylcholinesterase, the enzyme that breaks down acetylcholine, elevating ranges of the neurotransmitter tied to reminiscence and cognitive perform.[30] Practically all the human medical analysis at this dose vary comes from older adults with cognitive impairment, the place 200mcg to 400mcg taken twice each day improved reminiscence and cognitive scores over 8 to 24 weeks.[31] The dose right here lands inside that per-dose vary, although the analysis inhabitants is a world away from a wholesome pre-workout consumer chasing mind-muscle connection, so consider this as a well-studied nootropic mechanism borrowed from a unique context quite than a pre-workout-specific profit.

Rauwolscine (Alpha-Yohimbine) – 1mg

Oh boy, right here we go! Rauwolscine, additionally referred to as alpha-yohimbine, is a extra receptor-selective isomer of the better-known stimulant yohimbine, and it really works by blocking alpha-2 adrenergic receptors that in any other case put the brakes on fats launch from fats cells.[32]

Direct human trials on rauwolscine itself are nonetheless missing, so most of what is identified is extrapolated from yohimbine, its shut relative: in a single 21-day trial in soccer gamers, 20mg per day of yohimbine considerably lowered physique fats proportion with out affecting muscle mass or efficiency check outcomes.[33] Be aware that this mechanism will get blunted by meals, since a standardized meal fully blocked yohimbine’s fat-mobilizing impact in managed testing.[34] At 1mg, Excessive’s dose sits on the decrease finish of what is sometimes used, in line with rauwolscine’s higher efficiency relative to yohimbine HCl. Most customers will get pleasure from this dose — an excessive amount of will be, properly… an excessive amount of. 1mg is excellent.

SuperHuman Jacked: The Development Swap

Jacked was a GNC unique in its earlier type. On this relaunch, Alpha Lion repositioned it round a dual-peptide expertise stack as a substitute of what Darin Decker candidly referred to as a “kitchen sink” formulation on our episode collectively.

Just a few dose variations from Authentic earlier than heading into the brand new components: L-Citrulline sits increased at 6,000mg, whereas L-Tyrosine is available in decrease at 1,000mg (versus Authentic’s 1,500mg). Betaine Anhydrous (2,500mg), Taurine (1,000mg), Choline and Vitacholine® (200mg/500mg), Vitamin B12 (500mcg), and Black Pepper Extract (10mg) all match Authentic’s doses.

Vitamin B6 lands on the similar 50mg as Authentic, however in a unique chemical type, Pyridoxal-5′-Phosphate right here versus Pyridoxine HCl in Authentic. Jacked additionally skips Agmatine Sulfate and Vincamine totally, provides a novel 150mg of Sodium from Pink Himalayan Sea Salt, and carries much less complete caffeine than Authentic at 242mg versus 325mg. Now, the actives that make Jacked its personal product:

PeptiStrong® (Fava Bean Protein Hydrolysate) – 2,400mg

PeptiStrong® is a fava bean (Vicia faba) protein hydrolysate recognized by an AI-driven peptide discovery course of, and it is one of many extra human-research-backed novel peptides within the pre-workout house. In a randomized, placebo-controlled trial utilizing this actual 2,400mg dose, 30 wholesome males who took PeptiStrong for 14 days confirmed considerably higher energy restoration over the 72 hours following an intense resistance exercise, together with lowered muscle fatigue and suppressed plasma myostatin, a protein that places the brakes on muscle development.[35]

A separate 56-day trial in 72 women and men discovered considerably higher leg energy beneficial properties from resistance coaching mixed with the hydrolysate in comparison with coaching alone, together with improved muscular endurance.[36]

Alpha Lion positions this as a no-loading-phase addition(which is smart given the elimination of creatine), and the dose right here matches precisely what’s truly been studied.

PeptiPump® (Lentil Protein Hydrolysate Powder) – 200mg

PeptiPump® is a companion peptide fraction derived from lentil protein, dosed right here at 200mg alongside PeptiStrong’s a lot bigger 2,400mg. Bioactive peptides from legume and dairy proteins have an actual analysis historical past within the ACE-inhibitory peptide house, the place sure sequences have been proven to assist blood vessel perform in different contexts, however we nonetheless haven’t any printed analysis particular to PeptiPump itself.

Till PeptiPump-specific knowledge is printed by Nuritas, its inclusion right here rests on category-level bioactive-peptide plausibility quite than a demonstrated impact of its personal. With that mentioned, we’re led to imagine it is an ACE inhibitor, enjoying “protection” for the pumps. When new knowledge comes, PricePlow would be the first one on it, and it will be on our major PeptiPump web page.

Tensia™ (Lactiplantibacillus plantarum DSM 21380) – 20mg

Tensia™ is the ingredient Alpha Lion is most enthusiastic about on this reformulation, and Mike and Ben agreed on our podcast that it is a legitimately novel discover: a probiotic pressure, previously categorised as Lactobacillus plantarum earlier than a genus-wide reclassification, being utilized in sports activities diet for what seems to be the primary time.

The pressure has an actual publication historical past, simply not in a pre-workout context. Human trials out of Estonia have studied it delivered by probiotic cheese and yogurt, usually in adults with elevated blood strain, the place three-week consumption durations confirmed reductions in blood strain alongside a clear security profile throughout age teams.[37] None of that analysis measured pump, nitric oxide, or train efficiency instantly, and none of it used a standalone powder dose just like the 20mg included right here. The hope right here is that it is truly utilizing the intestine to metabolize lactic acid, turning it into one thing extra anabolic.

The blood-pressure angle is no less than mechanistically pump-adjacent, however that is genuinely new territory for the ingredient, and it is one we’ll be anticipating devoted sports-nutrition analysis on because it develops.

What’s Modified

Jacked’s reformulation goes deeper than Authentic’s or Excessive’s. This is the label-to-label comparability in opposition to its earlier formulation:

Creatine Monohydrate and HMB are each gone: The earlier formulation’s 2,500mg Creatine Monohydrate and 1,786mg Calcium HMB (offering 260mg of calcium) do not seem wherever on the brand new label. In the event you have been shopping for Jacked particularly for both of these, this model would not have them, and you may want your creatine + HMB individually.
The ElectroPrime® and NutriGP® blends have been eliminated: That drops the earlier formulation’s magnesium and potassium totally, together with most of its chloride. Sodium survives, now sourced solely from Pink Himalayan Sea Salt at a barely increased 150mg.
Citrulline type and dose each modified: The previous formulation’s 4,500mg of two:1 Citrulline Malate labored out to roughly 3,000mg of precise citrulline. The brand new formulation’s 6,000mg of pure L-Citrulline doubles that.
PeptiStrong doubled, from 1,200mg to 2,400mg (medical dose), and Betaine Anhydrous elevated from 1,600mg to 2,500mg (additionally a extra clinically-studied dose).
A brand new B-vitamin stack was added: Niacin, Vitamin B6, and Vitamin B12 are all new to this formulation.
PeptiPump and Tensia are model new additions, rounding out the dual-peptide-and-probiotic angle lined above.
Caffeine greater than doubled: the earlier SXT™ Vitality System delivered a 100mg complete caffeine yield per scoop. The brand new SUPERHUMAN ENERGY® System delivers 242mg per scoop.
Serving dimension simplified: the previous label confirmed each a 42-serving rely (1 scoop, 17.1g) and a 21-serving rely (2 scoops, 34.1g) on the identical panel. The brand new label is one clear 19.3g scoop as 1 of 21 servings.

That is essentially the most considerably rebuilt formulation within the relaunch. The place Authentic saved its core amino stack absolutely intact, Jacked drops two long-established muscle-building actives in favor of a more recent peptide-and-probiotic method paired with a considerably stronger vitality system.

It’s going to be attention-grabbing to see how this one lands with its userbase, as Alpha Lion’s solely creatine-based pre-workout is now simply the Amazon-based SuperHuman Core pre-workout.

SuperHuman Burn: The Warmth Swap

Burn is Alpha Lion’s 2-in-1 fat-burning pre-workout, and it is the one formulation on this complete relaunch that did not change. On our podcast, Darin mentioned Burn is “staying precisely the best way it’s, only a new feel and look”, and each Ben and Mike agreed on air that they would not have touched it both, calling the formulation near timeless. Identical doses, similar label, simply the brand new crimson packaging and switch-based positioning.

Burn skips the B-vitamin stack, Agmatine Sulfate, and Vincamine totally, and it is the one product within the line thus far with none Betaine Anhydrous in any respect (though there may be some fats loss analysis on it, so stacking it again in is not a horrible thought).

L-Citrulline (4,000mg) and Beta-Alanine (3,200mg) match Authentic precisely, whereas L-Tyrosine (1,000mg) and Taurine (500mg) each are available in decrease than Authentic’s 1,500mg and 1,000mg. Choline is dealt with in a different way too: Burn lists one flat 1,000mg Choline Bitartrate line, twice the quantity. Complete caffeine lands at 304mg, slightly below Authentic’s 325mg. What makes Burn its personal product is the thermogenic stack layered on high:

MitoBurn® (L-β-aminoisobutyric Acid) – 500mg

NNB Diet’s MitoBurn® delivers L-β-aminoisobutyric acid (BAIBA), a molecule your muscle tissues naturally produce throughout train and launch into the bloodstream as a signaling compound typically referred to as a myokine. In mouse analysis, BAIBA promotes fats browning, the conversion of energy-storing white fats towards the extra metabolically lively brown fats kind, and boosts fatty acid burning within the liver.[38] In people, increased circulating BAIBA has been linked to decrease fats mass in observational analysis, together with in coronary heart failure sufferers tracked by DEXA scan.[39] Practically all of this proof describes BAIBA your physique makes by itself by coaching. Supplementing it instantly at a hard and fast 500mg dose, quite than ready for train to lift it naturally, is MitoBurn’s core premise, and we did not discover a managed human trial testing oral BAIBA supplementation in opposition to a placebo for fat-loss outcomes particularly.

SantEnergy™ Nu (Eriodictyon californicum) – 400mg

SantEnergy™ Nu is a proprietary extract of Yerba Santa (Eriodictyon californicum) standardized to no less than 4% homoeriodictyol, one of many plant’s attribute flavonoids. SantEnergy Nu itself has truly been studied in people, too: In a randomized, double-blind, placebo-controlled trial, chubby and overweight ladies supplemented with 400 milligrams of SantEnergy Nu twice each day for 12 weeks. Among the many ladies with weight problems, supplementation considerably lowered physique weight and physique fats in comparison with placebo, whereas the mixed overweight-and-obese inhabitants confirmed solely a nonsignificant development towards decrease physique weight. [40]

The mechanistic knowledge is attention-grabbing for a pre-workout as properly. Yerba Santa extract demonstrated dose-dependent binding to the adenosine A2A receptor and elevated locomotor exercise in C. elegans, suggesting a doable stimulant-adjacent metabolic impact. Nonetheless, these findings shouldn’t be confused with proof of acute train enhancement in people. Burn provides 400 milligrams per serving, matching every particular person dose used within the medical trial, though the research administered that dose twice each day quite than as a single pre-workout dose.

CaloriBurn GP® (Grains of Paradise Extract) – 40mg

CaloriBurn GP® is a standardized extract of grains of paradise additionally from NNB Diet, dosed right here to ship 6-paradol, the spicy compound behind its thermogenic status. In a randomized human trial utilizing this actual 40mg dose, grains of paradise extract elevated whole-body vitality expenditure.[41]

Animal analysis backs up the mechanism, displaying that 6-paradol instantly triggers sympathetic nerve exercise and warmth manufacturing in brown fats tissue.[42] In plain phrases, this ingredient’s real-world impact could rely on how a lot lively brown fats you are carrying, which varies fairly a bit individual to individual and tends to say no with age.

There’s numerous interaction between MitoBurn and CaloriBurn too: MitoBurn can improve BAT, and CaloriBurn can activate it.

Sensoril® Ashwagandha Extract – 250mg

Sensoril® Ashwagandha Extract, standardized from Withania somnifera root and leaf, is greatest identified in sports activities diet for a 12-week trial the place 500mg per day improved 1-rep-max squat and bench press beneficial properties alongside a structured resistance coaching program, in comparison with placebo.[43] Burn’s 250mg dose is half of what that trial used, so consider this extra as using on ashwagandha’s broader stress-and-recovery status than a assure of the identical energy beneficial properties at half the studied quantity.

Extra importantly for weight reduction, ashwagandha is well-known for modulating cortisol, so your physique can probably get out of its prolonged flight-or-fight response, chill out, and get again to burning fats.

GBBGO® (Gamma Butyrobetaine HCl) – 5mg

GBBGO® provides gamma-butyrobetaine (GBB), the direct metabolic precursor your physique converts into L-carnitine within the ultimate step of carnitine synthesis. That conversion pathway is well-established biochemistry, and at 5mg the dose here’s a small addition relative to the remainder of the label. To us, that is good, as a result of it induces some critical sweating at increased doses.

Some formulators embody GBB alongside carnitine-supporting components on the speculation that supplying the precursor instantly may match the pathway extra effectively than carnitine alone, whereas others simply look to it for a uncooked thermogenic that will get the sweat shifting. Both manner, it is a pleasant starter dose that ought to kick issues up, however not tear you down.

Rauwolscine (Alpha-Yohimbine) – 1mg

Rauwolscine, branded right here as Alphahim® quite than Excessive’s Alfabin® (the identical generic ingredient from a unique provider), seems on the similar 1mg dose. We lined its mechanism and proof within the Excessive part above, and nothing concerning the science modifications right here.

SuperHuman Pump: The Non-Stim Swap

Pump is Alpha Lion’s zero-caffeine possibility, constructed for lifters who prepare late, are delicate to stimulants, or simply desire a pump-and-hydration formulation with out including to their each day caffeine complete.

Pump carries no caffeine in any respect. L-Citrulline runs a lot increased than Authentic at 8,000mg (versus 4,000mg), and Agmatine Sulfate is increased too at 1,500mg (versus 1,000mg). Beta-Alanine (3,200mg), Taurine (1,000mg), Choline and Vitacholine® (200mg/500mg), and Vincamine (10mg) all match Authentic’s doses precisely, and we can’t repeat that science right here. Vitamin B6 is available in decrease at 28mg and, like Jacked, makes use of the Pyridoxal-5′-Phosphate type quite than Authentic’s Pyridoxine HCl. Pump skips Niacin totally, the identical as Burn. Huperzia Serrata Extract seems on the similar 20mg, 1% Huperzine-A spec lined within the Excessive part above. The true differentiator is a four-part electrolyte addition Authentic would not have in any respect: Magnesium (45mg), Chloride (250mg), Sodium (160mg), and Potassium (210mg), supporting the hydration angle Pump has constructed its status on.

Lion’s Mane Mushroom Extract (Hericium erinaceus) – 600mg

Lion’s Mane Mushroom Extract is a mushroom lengthy utilized in conventional Chinese language and Japanese medication, and its analysis facilities on two compound lessons, hericenones and erinacines, each of which stimulate nerve development issue (NGF) manufacturing related to neuron well being and cognitive perform. In a randomized, placebo-controlled trial in wholesome adults aged 18 to 45 utilizing 1.8 grams per day, a single dose improved response velocity on a Stroop cognitive check inside an hour, with a development towards lowered stress after 28 days of continued use.[44] Pump’s 600mg dose is roughly a 3rd of what that trial used, and many of the deeper cognitive analysis on Lion’s Mane comes from older adults with identified cognitive impairment quite than wholesome exercisers, so the studied results do not map onto this actual use case completely.

AstraGin® (Astragalus membranaceus and Panax notoginseng) – 50mg

AstraGin® is a standardized mix of Astragalus membranaceus and Panax notoginseng root extracts marketed as an absorption enhancer quite than an lively ingredient with its personal major impact. In a randomized, double-blind crossover trial in wholesome adults utilizing this actual 50mg dose alongside 5 grams of oral arginine, AstraGin considerably elevated arginine absorption into the bloodstream and improved the arginine-to-ADMA ratio, a marker tied to how a lot arginine is obtainable for nitric oxide manufacturing, by 167%.[45] Downstream markers of precise nitric oxide manufacturing trended upward too however did not attain statistical significance on this research, so the arginine-absorption enhance is the best-supported piece of AstraGin’s case right here, with the pump profit itself one step eliminated quite than instantly measured.

What’s Modified

Evaluating to the earlier Pump formulation:

HydroPrime® (Glycerol) is gone: the earlier formulation’s 3,000mg of glycerol powder, the ingredient this product was initially constructed round for hydration, would not seem wherever within the new label.
AlphaSize® (Alpha-GPC) was eliminated: the earlier formulation’s 300mg of Alpha-GPC, a premium choline supply, is changed by the identical Choline Bitartrate and Vitacholine® construction utilized in Authentic (200mg/500mg).
Niacin and S7™ are each gone: Niacin was beforehand included at 12.5mg NE, and the S7™ mix at 150mg. Neither carries over.
Citrulline switched from malate to pure type: the previous formulation’s 8,000mg of two:1 Citrulline Malate is now 8,000mg of pure L-Citrulline, meaningfully rising the precise citrulline delivered despite the fact that the headline quantity seems to be unchanged.
Huperzine A elevated: from 150mcg of Huperzine A to a 20mg Huperzia Serrata Extract standardized to 1% Huperzine-A, a bigger uncooked dose.
A brand new B-vitamin, amino acid, and nootropic stack was added: Vitamin B6, Vitamin B12, Agmatine Sulfate, Taurine, and Vincamine are all new to this formulation.
The electrolyte mix was restructured: Sodium dropped from a 350mg Pink Himalayan Sea Salt supply to 160mg (now paired with a newly disclosed 250mg Chloride line), Potassium elevated from 75mg to 210mg, and Magnesium elevated barely from 35mg to 45mg.
Serving dimension simplified: the previous label confirmed each a 42-serving (1 scoop, 8.75g) and 21-serving (2 scoops, 17.5g) rely on one panel. The brand new label is a single 20.3g scoop as 1 of 21 servings.

This one’s for individuals who need large citrulline doses and are not into different novel pump components. Shedding glycerol and Alpha-GPC is a departure from what made the unique Pump formulation distinct, however the brand new B-vitamin, agmatine, and electrolyte additions construct a unique type of hydration-and-focus case of their place.

Stacking & Selecting Your Swap

With 5 formulation constructed round 5 completely different objectives, selecting the correct SuperHuman comes right down to matching the change to the session.

Product
Complete Caffeine
Standout Ingredient(s)
Finest For

SuperHuman Authentic
325mg
Full B-vitamin and focus stack
On a regular basis coaching, each day driver

SuperHuman Excessive
376mg
Bitter Orange, Rauwolscine
Stim veterans, max-intensity days

SuperHuman Jacked
242mg
PeptiStrong, PeptiPump, Tensia
Muscle constructing, no loading part

SuperHuman Burn
304mg
MitoBurn, CaloriBurn GP
Fats loss alongside coaching

SuperHuman Pump
0mg
AstraGin, Lion’s Mane
Stim-free coaching, evening periods

On our podcast, Darin shared his personal stacking routine: taking SuperHuman Burn within the morning carries him by the day with no need extra caffeine till round 3pm, because it’s dosed decrease than his typical vitality drink behavior. That is the type of use case these 5 formulation are constructed round: decide the one which matches your schedule and aim as a substitute of leaning on one aggressive formulation for each session.

Just a few mixtures price calling out. Lifters coaching twice in at some point would possibly attain for SuperHuman Authentic or Excessive for a morning session and SuperHuman Pump for a night one, since Pump carries zero caffeine and will not intervene with sleep. Anybody chasing a physique recomposition aim would possibly rotate between SuperHuman Burn and SuperHuman Jacked relying on whether or not that day’s session is targeted on chopping or constructing.

One apparent warning price stating: Authentic, Excessive, Jacked, and Burn all comprise caffeine, so do not stack two of those in the identical session except you’ve got executed the mathematics in your complete each day consumption first.

Conclusion: 5 Switches, One Commonplace

Alpha Lion rebuilt the vitality system beneath SuperHuman’s new crimson packaging and gave each formulation within the line a purpose to exist by itself. The formulation that first constructed the model’s status continues to be recognizable in Authentic’s core amino and pump stack, however the SuperHuman Vitality® System, the added B-vitamin and focus components, and the change from citrulline malate to pure citrulline all level to a real formulation replace quite than a label refresh.

Whether or not you are after Authentic’s daily-driver steadiness, Excessive’s high-stim ceiling, Jacked’s muscle-building peptide stack, Burn’s untouched fat-loss formulation, or Pump’s stim-free pump-and-focus combo, the lineup is constructed so you may decide a change as a substitute of settling for a one-size-fits-all pre-workout. All 5 land in GNC and Vitamin Shoppe alongside Alpha Lion’s typical on-line availability, and you will not miss these crimson tubs.

Test PricePlow for pricing and availability throughout the complete SuperHuman lineup because it rolls out, and join Alpha Lion worth alerts to know the second your taste and formulation of alternative is again in inventory.