Study identifies TAK1 gene as a key brake on cancer immunotherapy
Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism ...
Tag: gene
Gene Therapy for Children With Rare ‘Bubble Boy Disease’ Proves Effective After Long-Term Follow-Up
The 62 children who were found to have the rare "Bubble Boy disease" as babies and toddlers between 2012 and ...
Condensate-based strategy protects synthetic gene circuits across cell generations
Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can ...
Brain’s metabolic shift explains why APOE4 gene carriers have higher Alzheimer’s risk
Loss of sortilin or the presence of apoE4 renders neuronal mitochondria insensitive to inhibition of LCFA import. Credit: Nature Metabolism ...
Sarepta to seek approval for gene therapy in rare muscular dystrophy
An experimental gene therapy from Sarepta Therapeutics increased levels of the gene missing in an ultra-rare form of muscular dystrophy, ...
First Successful Gene Therapy for Huntington’s Disease Slows Disease Progression by 75%
An experimental gene therapy developed by uniQure has, for the first time, shown a dramatic slowing of Huntington's disease progression ...
Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure
Background and objectives Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with substantial morbidity ...
Dr. Michael Piepkorn on How the Discovery of the p16 Gene Transformed Familial Melanoma Diagnosis
The discovery of the p16 gene was a significant turning point in understanding familial melanoma. This development was primarily responsible ...
Large-scale gene analysis identifies new biomarkers and drug targets for lung adenocarcinoma
Graphical abstract. Credit: Cancer Cell (2025). DOI: 10.1016/j.ccell.2025.07.011 By analyzing tens of thousands of genes, proteins, and protein modifications in ...
New research identifies critical gene for treatment
Amyotrophic lateral sclerosis (ALS) - which you may know as the disease that affected Stephen Hawking - is a fatal ...
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