New study challenges the traditional view of gene switches
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, ...
Tag: gene
Scientists map cancer mutations in EGFR gene, revealing drug resistance paths
By combining advanced gene editing techniques, scientists identified key mutations that influence tumor growth and drug resistance in lung cancer, ...
PTC Therapeutics Wins First FDA Approval for a Gene Therapy Dosed Directly Into the Brain
An ultra-rare enzyme deficiency that keeps infants from achieving proper muscle function among other developmental delays now has its first ...
MIT team creates efficient technique for identifying causal gene relationships
By studying changes in gene expression, researchers learn how cells function at a molecular level, which could help them understand ...
Stem cells can tailor their role in gene therapy based on the underlying disease, study suggests
Credit: CC0 Public Domain RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt ...
Gene editing approach helps launch first-in-human clinical trial for rare genetic disease
Credit: Unsplash/CC0 Public Domain A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and ...
On Heels of Positive Parkinson’s Gene Therapy Data, MeiraGTx Looks Ahead to Pivotal Test
A MeiraGTx Holdings gene therapy for Parkinson’s disease has preliminary data from a small clinical trial showing the one-time treatment ...
Differential gene expression linked to alcohol use disorder, offering new treatment possibilities
New study reveals gene expression differences in brain regions tied to addiction, highlighting pathways for innovative alcohol use disorder treatments ...
Disrupting Asxl1 gene prevents T-cell exhaustion to improve immunotherapy, researchers discover
Core epigenetic regulators in maintaining therapeutic durable multipotent Tpex populations. Credit: Science (2024). DOI: 10.1126/science.adl4492 Immunotherapy, using a patient's own ...
Study reveals key role of TRIO gene in epileptic encephalopathies
Defective migration of MGE-derived cortical INs in Trio–/– embryos. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02742-y What are the molecular and ...
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