Consuming breakfast is a surprisingly important a part of well being, and many people love to clean it down with a glass of OJ. Maybe you’re consuming it as a result of your blood sugar is low, you need vitamin C to spice up immunity otherwise you merely just like the style.
Whereas some dietary details about orange juice are fairly well-known and simple — just like the aforementioned appreciable vitamin C content material — the results it has in your physique aren’t as clear as beforehand thought, in response to a 2025 examine. Extra particularly, what you reap from the drink could rely in your weight.
“In accordance with the examine authors, consuming orange juice activated totally different genes in ‘obese’ members than ‘regular weight’ members, though they by no means outline what they imply by these phrases within the examine,” stated Christine Byrne, a dietitian and the proprietor of Ruby Oak Vitamin in Raleigh, North Carolina. “In the event that they have been utilizing BMI standards, ‘regular weight’ means anybody with a BMI of 18.5 to 24.9, whereas ‘obese’ means anybody with a BMI of 25-29.9.”
(BMI and its youthful sibling, the BRI, have since been debunked, however are nonetheless extensively used. Descriptors like “regular,” “obese” and “larger” are in quotations for the previous motive.)
Again to orange juice and weight. With these findings, does a glass of OJ nonetheless match into your well being objectives? Let’s discover out. HuffPost talked to registered dietitians about this examine, how orange juice could have an effect on your physique and what the real-life implications are.
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How Orange Juice Impacts Individuals With ‘Larger’ Physique Weights
In individuals with “larger” physique weights, the examine discovered that orange juice prompts genes concerned in fats metabolism.
“Vitamin C, typically, helps to spice up metabolism by serving to convert fats into vitality,” defined Kathryn Johnson, a registered dietitian and the vitamin director at Consuming Restoration Middle. “It additionally aids in carnitine manufacturing, which transports fat to cells for burning.”
How Orange Juice Impacts Individuals With ‘Regular’ Physique Weights
In individuals with “regular” physique weights, the examine discovered that orange juice affected genes that regulate irritation, which a 2024 examine calls “the reason for all illnesses.”
The reasoning comes all the way down to your physique’s priorities, or the place you most want the vitamins.
“We all know that when persons are malnourished or undernourished, it may well have an effect on issues like development, your menstrual cycle and adequately combating an infection,” Johnson stated. “So whereas vitamin C nonetheless supplies the acknowledged advantages above, it takes extra vitality to burn fats than carbohydrates. That’s decrease on the checklist of what the physique is ready to do.”
Larger on the physique’s checklist, she continued, are extra medically essential issues, resembling getting oxygen to your cells, pumping the guts and transporting blood.
This isn’t to say that each one individuals with a “regular” and even “decrease” physique weight are malnourished or undernourished.
Well timed aspect be aware: The Worldwide Diabetes Federation formally acknowledged Sort 5 diabetes as a illness in 2025, and it usually impacts individuals who skilled long-term malnourishment, particularly of their youth.
The Actual-Life, On a regular basis Implications Of This Examine’s Findings
In accordance with Johnson, the purpose of the examine is that this: “Your physique features extra successfully when adequately nourished.” In different phrases, it doesn’t have to fret about finishing up different features first.
This fact extends past orange juice: Johnson added how some drugs, minerals and nutritional vitamins don’t work as successfully when the patron is undernourished or malnourished.
However that’s about it. Don’t take data from the examine that it’s not giving.
“Frankly, I don’t assume there’s any real-life takeaway from a examine like this,” Byrne stated.
Why? As a result of the examine solely had 20 members, they have been in a comparatively small age vary (21 to 36 years outdated) and gene expression, not an end result, was assessed.
“Completely different genes play a job in numerous organic processes, however activating sure genes doesn’t assure that something will occur,” Byrne continued. “For instance, activating genes concerned with fats metabolism doesn’t imply that you just’re going to burn extra fats.”
She added that the connection between vitamin and gene expression is one thing that we’re solely starting to know. These research present an proof base, however it’s too early to attract an correct, confirmed conclusion or advice.
The Takeaway: Our bodies Are Completely different And Have Completely different Wants
We might be remiss to disregard that this analysis conclusion illustrates how our bodies are totally different, have totally different wants and reply to vitamins otherwise.
“The concept totally different meals have an effect on individuals otherwise is an effective takeaway from this examine — and possibly the one related takeaway for most individuals,” Byrne stated.
Different examples of how the identical meals can have totally different results embody:
Alongside these traces, we can’t assume somebody’s well being by their physique measurement. That has at all times been true for a lot of causes, plus one other current one.
“With elevated GLP-1 drugs, we’re seeing extra sufferers whose BMI could fall into the ‘regular’ class, however attributable to weight reduction [and the] quantity of meals/protein that they can absorb, their physique is presenting as undernourished,” Johnson stated.
For sure, our bodies and vitamin (and even orange juice) are extra advanced than beforehand thought, and analysis continues to be ongoing. That range is a wonderful, essential factor we are able to’t ignore.

