20g Protein, Creatine, and 125mg Cognizin® Citicoline

MOSH, the brain-health snack model co-founded by Maria Shriver and Patrick Schwarzenegger, simply launched its new Excessive Protein Bar line at greater than 2,000 Goal shops nationwide! Three flavors can be found: Peanut Butter Cup, Chocolate Sea Salt, and Oatmeal Chocolate Chip. After years of constructing the model round the concept meals ought to help your mind alongside your physique, MOSH now has the shelf presence to make that case at scale.

A Mind Model with Greater Protein

Every bar delivers 200 energy, 20 grams of protein from a mix of dairy proteins, simply 3 grams of sugar, and 6 grams of fiber. The MOSH Excessive Protein Bar separates itself from most choices within the aisle with its Premium Mind Mix: Creatine Monohydrate, Natural Lion’s Mane, flaxseed, Ashwagandha (as KSM-66®), Nutritional vitamins D3 and B12, and 125mg of Cognizin® citicoline per bar to help cognitive well being and wholesome mind perform.

We have lined the unique MOSH protein bar earlier than, and the Excessive Protein line marks a transparent evolution: protein climbs to twenty grams, creatine monohydrate joins the formulation, and the clean-label method stays intact with no artificial sweeteners and gluten-free certification. For a more in-depth have a look at the analysis behind the citicoline, see our Cognizin® Citicoline ingredient information linked above.

MOSH additionally donates to Alzheimer’s analysis with each buy, in step with its positioning as “The Mind Model”. Whether or not you seize one pre-workout, as a noon snack, or rather than a rushed meal, the pitch is constant: strong macros and brain-supporting elements in each bar.

This text will get into the science, main with Cognizin® citicoline, the mind choline. First, let’s examine in on costs and availability:

MOSH Excessive Protein Bar Vitamin Info

Energy – 200

Complete Fats – 8g

Complete Carbohydrate – 23g

Dietary Fiber – 6g

Complete Sugars – 3g

Protein – 20g

Nutritional vitamins and Minerals

Vitamin D3 – 3mcg (15% DV)

Vitamin B12 – 2.4mcg (100% DV)

Calcium – 110mg (8% DV)

Iron – 1.1mg (6% DV)

Potassium – 180mg (4% DV)

MOSH Excessive Protein Bar Components

Every 60g (2.11 oz) bar supplies the next:

Citicoline (as Cognizin®) – 125mg

Cognizin® Citicoline is a bioidentical molecule the physique produces naturally as an intermediate in phosphatidylcholine synthesis. Not like easier choline sources, it delivers each a choline element and a cytidine element. The mind will get two distinct precursors from a single compound.[1]

After ingestion, citicoline cleaves into choline and cytidine, which converts to uridine in peripheral circulation. Each cross the blood-brain barrier and are reassembled into CDP-choline inside mind cells.[2] The choline fraction helps acetylcholine synthesis, the neurotransmitter central to reminiscence and attentional perform, whereas additionally contributing to phosphatidylcholine manufacturing in neuronal membranes. Citicoline additionally helps wholesome ranges of dopamine and norepinephrine within the central nervous system.[3]

The structural results run deeper than neurotransmitter help alone. Analysis utilizing phosphorus magnetic resonance spectroscopy discovered that six weeks of citicoline supplementation elevated phosphodiesters within the frontal lobe, reflecting lively membrane synthesis and restore. The identical research famous vital will increase in phosphocreatine (+7%) and ATP (+14%) within the anterior cingulate cortex, suggesting citicoline helps keep the mind’s vitality reserves as properly.[4]

Cognizin® Citicoline is dubbed the The Mind Choline not simply because it supplies choline, however as a result of it additionally provides cytidine, which can be wanted for the synthesis of phosphatidylcholine

Human trials with bigger doses of Cognizin® add direct cognitive proof. A 28-day research in adolescent males discovered that 250mg to 500mg every day improved consideration and psychomotor pace versus placebo, with greater weight-adjusted doses predicting higher accuracy on cognitive duties and lowered impulsivity.[5] Analysis in wholesome adults utilizing 500mg every day additionally discovered enhancements in psychomotor vigilance and visible working reminiscence in comparison with placebo.[6] A 12-week randomized managed trial utilizing 500mg Cognizin® every day in older adults with age-associated reminiscence impairment discovered considerably larger enhancements in episodic and composite reminiscence in comparison with placebo.[7]

Every MOSH bar delivers 125mg of Cognizin®, a strong every day dose that helps cognitive well being and wholesome mind perform. Kyowa’s structure-function help for focus, consideration, and accuracy is generally grounded in 250mg every day (two bars), so these focusing on these particular advantages can attain that threshold with a second bar on higher-demand days.

For instance, a companion research to the 28-day trial mentioned above discovered that 250mg citicoline taken every day by wholesome grownup girls particularly improved attentional efficiency versus placebo[8] — much more purpose to eat two bars!

Cognizin® pairs naturally with the remainder of MOSH’s Mind Mix. Creatine monohydrate addresses mind vitality via the phosphocreatine system, reinforcing the identical ATP manufacturing pathways that citicoline helps in frontal lobe tissue. Lion’s Mane and ashwagandha contribute to neuroplasticity and stress-related cognitive perform, whereas flaxseed, vitamin B12, and vitamin D3 present extra dietary help for neurological well being.

For a full have a look at Cognizin®’s analysis base, see our Cognizin® Citicoline: The Mind Choline information.

Protein Mix (Whey Protein Isolate, Whey Protein Focus, Milk Protein Isolate) – 20g Protein

MOSH’s 20g protein comes from three dairy fractions that contribute throughout completely different phases of the amino acid absorption curve:

Whey Protein Isolate

Whey protein isolate (WPI) is the purest and fastest-digesting element, with protein content material exceeding 90% of dry weight and lactose under 1%.[9] This fast digestion drives a pronounced spike in plasma leucine, the set off for mTOR signaling and downstream muscle protein synthesis.[10] A randomized managed trial discovered that WPI ingested instantly post-exercise activated mTOR and different muscle-supporting mechanisms inside 2 hours in exercised muscle.[11]

Whey Protein Focus

Whey protein focus (WPC) provides complementary dairy protein at anyplace from 34 to 80% protein by dry weight alongside some lactose and fats (the quantity relying on degree of processing). It typically shares WPI’s leucine-rich amino acid profile, offering extra protein to spherical out the whole dose.

Milk Protein Isolate

Milk protein isolate (MPI) preserves complete milk’s pure protein ratio: roughly 20% whey and 80% casein. The casein fraction releases amino acids regularly, extending anabolic help properly past the preliminary leucine spike. Analysis in rats discovered that mixed milk protein produced the best cumulative fractional synthesis charge post-exercise in comparison with both whey or caseinate alone, in line with a chronic anabolic response.[12] This sustained supply matches a bar format, the place fat and fiber naturally sluggish gastric emptying.

At 20g complete, the mix matches the dose discovered to maximally stimulate myofibrillar MPS in resistance-trained males, and it really works alongside MOSH’s creatine monohydrate to help muscle vitality and restoration.[13]

Creatine Monohydrate

Creatine monohydrate is essentially the most researched efficiency and cognitive complement in sports activities vitamin. After uptake, it combines with phosphate to kind phosphocreatine (PCr), quickly regenerating ATP when vitality demand spikes. The mind is among the many physique’s most energy-intensive organs, and creatine’s help for cerebral ATP reserves matches MOSH’s brain-health focus naturally.[14]

A scientific assessment of randomized managed trials discovered creatine supplementation improved short-term reminiscence and reasoning in wholesome adults,[15] and a meta-analysis discovered the strongest reminiscence enhancements in adults aged 66 to 76.[16]

The dose in MOSH bars is not disclosed and sure falls under the 3g to 5g every day threshold related to cognitive and efficiency analysis. Consider every bar as a helpful dietary contribution to complete creatine shops, with a standalone creatine complement filling the hole for these focusing on full results.

Value noting: citicoline has been proven to independently increase frontal lobe phosphocreatine (+7%) and ATP (+14%), making these two elements complementary inside the identical vitality pathway.[4]

Ashwagandha (as KSM-66®)

KSM-66® is a full-spectrum ashwagandha root extract standardized to a minimal 5% withanolides, the steroidal lactones related to its adaptogenic exercise. Analysis suggests the extract works largely via modulation of the hypothalamic-pituitary-adrenal (HPA) axis, supporting a wholesome cortisol response beneath bodily and psychological stress.

Kyowa Hakko USA earns 4th patent for Cognizin Citicoline, additional validating visible consideration & cognitive efficiency advantages. New IP covers strategies for enhancing consideration, motor perform & processing pace.

A 60-day, double-blind, placebo-controlled trial in 64 pressured adults discovered that KSM-66 at 300mg twice every day produced a 27.9% discount in serum cortisol and vital enchancment throughout all stress-assessment scales versus placebo.[17] A separate KSM-66 trial in adults with gentle cognitive impairment discovered enhancements in rapid reminiscence, government perform, sustained consideration, and information-processing pace versus placebo.[18]

The dose in MOSH’s formulation is not disclosed. KSM-66 research sometimes used 300mg to 600mg every day, so the contribution per bar cannot be confirmed. Alongside Cognizin® and creatine monohydrate, this extract provides a stress-management dimension to the Mind Mix that will reinforce cognitive efficiency over time.

Natural Lion’s Mane

Natural Lion’s Mane (Hericium erinaceus) produces hericenones in its fruiting physique, bioactive terpenoids related to nerve development issue (NGF) induction in neural cells.[19] NGF helps the upkeep of cholinergic neurons concerned in reminiscence and cognitive processing and may help neurogenesis within the hippocampus.[20]

Human trials have proven cognitive advantages at greater doses. A 16-week randomized managed trial (RCT) in adults with gentle cognitive impairment discovered considerably improved cognitive perform scores at 3g every day of H. erinaceus versus placebo.[21] A separate fruiting-body RCT discovered 12 weeks of supplementation improved MMSE scores versus placebo.[22]

MOSH’s dose is not disclosed, so these scientific outcomes cannot be assigned to this serving. The NGF pathway it targets overlaps meaningfully with Cognizin®’s help for acetylcholine synthesis, although, so collectively, they deal with complementary points of neuroplasticity inside MOSH’s Mind Mix.

Flaxseed

Flaxseed contributes three bioactive courses to the Mind Mix:

Alpha-linolenic acid (ALA),
the lignan secoisolariciresinol diglucoside (SDG), and
soluble fiber.

ALA, the first plant-derived omega-3, incorporates into cell membrane phospholipids, displacing arachidonic acid and supporting a wholesome inflammatory response.[23][24] SDG is transformed by intestine micro organism into the mammalian lignans enterolactone and enterodiol, offering antioxidant exercise.[23]

A meta-analysis of 62 RCTs discovered flaxseed supplementation considerably lowered complete ldl cholesterol, triglycerides, and LDL-C.[25] Systematic critiques additionally present significant blood strain reductions with prolonged use.[26] ALA’s function in cognition is early however promising, with observational information associating greater consumption with slower cognitive decline in some populations.[24]

The dose in MOSH is not disclosed. Scientific analysis sometimes makes use of large quantities (25g to 50g every day), so the contribution per bar cannot be confirmed. Nevertheless, seeing 6g fiber on this bar is an excellent signal, since so many individuals do not get sufficient fiber of their diets. Finally, within the Mind Mix, flaxseed provides potential cardiovascular and anti inflammatory dietary help to the cognitive stack.

Vitamin D3 – 3mcg (15% DV)

Vitamin D3 (cholecalciferol) is a fat-soluble prohormone that converts within the liver to 25-hydroxyvitamin D (25(OH)D), then to its lively kind, calcitriol, within the kidneys and peripheral tissues. The vitamin D receptor (VDR) is current on just about all cells of the immune system, and calcitriol modulates each innate and adaptive immune responses to help wholesome immune perform.[27][28] The VDR can be expressed all through neural tissue, and calcitriol is assumed to contribute to wholesome neurological perform.

Every bar supplies 3mcg (120 IU), contributing 15% of the every day worth, a dietary-level dose focusing on baseline dietary protection moderately than standalone supplementation. Analysis constantly hyperlinks low 25(OH)D to opposed outcomes throughout a number of organ programs, making deficiency avoidance the first scientific aim at this dose.[27] Within the Mind Mix, Vitamin D3 and Vitamin B12 function the dietary basis supporting the remainder of the cognitive stack. Sunshine’s at all times greatest, however if you happen to’re not getting sufficient solar, then cheap quantities of D3 are a fantastic thought.

Vitamin B12 – 2.4mcg (100% DV)

Vitamin B12 (cobalamin) is an important cofactor in one-carbon metabolism, the interconnected pathways that generate methyl teams for DNA synthesis, amino acid homeostasis, and homocysteine clearance. Inside cells, its lively coenzyme types (methylcobalamin and adenosylcobalamin) help programs that keep wholesome methylation exercise and forestall homocysteine from accumulating at ranges that will impair neurological perform.[29]

Ample B12 standing additionally helps myelin sheath integrity, the insulating layer crucial for fast neural signaling. Low B12 ranges are linked to larger cognitive impairment danger, and in poor people, B12 substitute confirmed MMSE rating enhancements in 78% of instances.[30]

Every bar supplies 2.4mcg, assembly 100% of the every day worth. That dietary baseline pairs naturally with citicoline’s acetylcholine synthesis and phosphatidylcholine help, serving to keep the neurochemical surroundings the Mind Mix targets.

Flavors Obtainable

This is an up-to-date checklist of all MOSH Excessive Protein Bar flavors:

Methods to Use

When to take it: One bar works properly as a whole snack between meals, pre/post-workout, or as a fast breakfast or lunch on a demanding day.
With or with out meals: Works fantastic by itself; pair with espresso or a protein shake if you happen to’re utilizing it as a full meal substitute.
Different notes: For these focusing on cognitive efficiency particularly, two bars convey Cognizin® to the 250mg degree cited in Kyowa Hakko’s focus-related claims.

Who It is For

Lively people: The 20g protein and creatine monohydrate mixture helps restoration and efficiency for anybody coaching commonly.
Busy professionals: Low sugar, excessive fiber, and the Premium Mind Mix make it a sensible seize on demanding days when sitting down for an actual meal is not an choice.
Mind health-focused customers: In case you’re proactively fascinated by long-term cognitive wellness, the Cognizin, Lion’s Mane, and ashwagandha mixture places MOSH in a special class than customary protein bars.

Conclusion: MOSH Excessive Protein Delivers on Each Fronts

MOSH Mind + Physique Gas Protein Bar is a standout purposeful meals product with 125mg Cognizin® Citicoline. That includes pure sweeteners and a Mind Mix with lion’s mane and KSM-66, it is excellent for satisfying your candy tooth whereas optimizing each bodily and psychological efficiency.

The MOSH Excessive Protein Bar does lots with 200 energy. Twenty grams of protein, 6 grams of fiber, 3 grams of sugar, creatine monohydrate, and 125mg of Cognizin® citicoline per bar — that is a significant mixture in a class the place most bars cease on the protein rely.

Cognizin® is the standout sponsored ingredient in MOSH’s Premium Mind Mix. At 125mg per bar (or 250mg throughout two bars), it helps cognitive well being and wholesome mind perform alongside the remainder of the Mind Mix. For the total story on Cognizin’s analysis, our Cognizin® Citicoline: The Mind Choline information is the place to begin, and for these centered on reminiscence and growing old, our protection of the Cognizin® reminiscence research in older adults provides essential scientific context.

4-packs are on sale at Goal, so MOSH Excessive Protein has the distribution to achieve individuals who’d by no means browse the complement aisle or head to a devoted vitamin retailer. For anybody prioritizing mind well being alongside their health routine, it is one of many extra full bars available on the market. Verify PricePlow under for present pricing and availability throughout all three flavors, and join alerts on what MOSH releases subsequent.