A rising variety of sufferers who want transfusions are asking for blood from unvaccinated donors, a tough request to honor, on condition that blood facilities don’t ask donors in the event that they’ve been vaccinated and don’t label blood based on vaccinated standing.
These requests typically delay care and, in some instances, hurt sufferers’ well being, based on a report printed late final week in Transfusion. Well being techniques must develop standardized insurance policies, embrace counseling, to deal with these requests, the report’s authors wrote.
The US blood provide is extremely secure, the authors wrote. Donations are fastidiously screened for HIV and different doubtlessly infectious microbes. There’s no proof that blood from unvaccinated folks is any safer than different blood.
The requests for “unvaccinated blood” elevated after the discharge of COVID-19 vaccines, which saved an estimated 20 million lives of their first 12 months of use, however which have been the topic of misinformation and conspiracy theories.
Vanderbilt College Medical Middle obtained 15 requests for unvaccinated blood from January 1, 2024, to December 31, 2025, based on the brand new report. The median age of sufferers was 17 years previous; greater than half have been youngsters.
Issues with ‘direct’ blood donations
Hospitals don’t have any technique to know if donated blood comes from vaccinated or unvaccinated donors, and there aren’t any assessments that may differentiate the blood of vaccinated from unvaccinated folks.
That leads some sufferers to ask for blood donation from explicit folks, equivalent to family members, whom they know to be unvaccinated. That’s a dangerous request, as a result of such “direct donations” from first-time donors usually tend to comprise doubtlessly dangerous pathogens in contrast with blood collected from individuals who donate usually, authors famous.
Within the examine, 13 sufferers obtained blood donated particularly for them by relations.
Two sufferers acquired a lot sicker after refusing a transfusion with customary blood. One developed anemia, which happens when folks don’t have sufficient iron of their blood. The opposite developed hemodynamic shock, a life-threatening situation wherein folks have insufficient blood movement and oxygen supply to tissues, which might trigger multi-organ failure.
These instances problem the declare by some anti-vaccine activists that insisting on blood from unvaccinated donors is “a benign or low-risk lodging,” authors wrote.
Lawmakers in a number of states—together with Connecticut, Kentucky, Montana, Oklahoma, Tennessee and Wyoming—have tried to mandate that sufferers have entry to blood transfusions from unvaccinated donors.
In January, an Oklahoma legislator went as far as to suggest that his state run its personal blood financial institution with a view to present blood donations from unvaccinated folks.
Up to now, not one of the payments has handed.

