Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Clinically accessible KRAS inhibitors primarily goal G12C, which is uncommon in PDAC and infrequently acquires resistance. Oncogenic KRAS inactivates RB1 ...
Tag: EGFR
Ivonescimab + chemotherapy improves progression-free survival in patients with EGFR+ NSCLC
Credit: Anna Tarazevich from Pexels Adding ivonescimab, a first-in-class bispecific antibody targeting both PD-1 and VEGF, to chemotherapy significantly prolonged ...
Scientists map cancer mutations in EGFR gene, revealing drug resistance paths
By combining advanced gene editing techniques, scientists identified key mutations that influence tumor growth and drug resistance in lung cancer, ...
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